Preparation and Evaluation of Blood Compatibility of Novel Epoxy-Modified Polyurethanes

نویسندگان

  • Atefeh Solouck Biomaterial Department, Faculty of Medical Engeneering, Amir Kabir University of Technology, Tehran, Iran
  • Hamid Yeganeh Polyurethane Department, Iran Polymer and Petrochemical Institute, Tehran, Iran
  • Mohammad Rafienia Medical Physics and BioMedical Engineering Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده مقاله:

      In order to prepare polyurethane elastomers with acceptable physical properties and good biocompatibility, novel polyurethane networks were synthesized via curing reaction of epoxy-terminated polyurethane prepolymers (EUPs) with hexamethylene diamine. EUPs were prepared from reaction of glycidol with NCO-terminated polyurethanes (ITPs). ITPs were also synthesized from reaction of one equivalent of either poly(tetramethylene ether)glycol or poly(ethylene glycol) with hexamethylene diisocyanate. Cytotoxcicity and blood compatibility were evaluated. All of the prepared polymers via this novel and simple method showed nontoxic behavior and acceptable blood compatibility.  

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عنوان ژورنال

دوره 4  شماره 4

صفحات  281- 288

تاریخ انتشار 2008-10-01

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